Adult POTS Articles

These articles appear in peer reviewed, scientific journals and are written by those active in researching POTS and other forms of dysautonomia.  When reading journal articles, it can be helpful to focus mainly on the abstract, introduction/background, and discussion section of the paper to get the main idea of the paper.


Resource LibrarySleep Disturbance Linked to Suicidal Ideation in Postural Orthostatic Tachycardia Syndrome.  2017. Science and Nature of Sleep.  Read Article


Health-Related Quality of Life and Suicide Risk in Postural Tachycardia Syndrome. 2017. Clinical Autonomic Research. Read Article


Objective Sleep Assessments in Patients with Postural Tachycardia Syndrome using Overnight Polysomnograms. 2016. Journal of Clinical Sleep Medicine.  Read Article


Orthostatic Intolerance Symptoms are Associated with Depression and Diminished Quality of Life in Patients with Postural Tachycardia Syndrome. 2016. Healthy and Quality of Life Outcomes. Read Article


Droxidopa in the Treatment of Postural Orthostatic Tachycardia Syndrome. 2016. American Journal of Therapeutics.  Read Article


Management of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia and Vasovagal Syncope. 2016. Arrhythmia & Electrophysiology Review.  Read Article


 The Complexity of Diagnosing Postural Orthostatic Tachycardia Syndrome: Influence of the Diurnal Variability. 2016. Journal of the American Society of Hypertension. Read Article


Spontaneous vs Nitroglycerin-Induced Vasovagal Reflex on Head-up Tilt: Are there Neuroendocrine Differences? 2016. Heart Rhythm.  Read Article


Postural Orthostatic Tachycardia Syndrome is associated with Platelet Storage Pool Deficiency. 2016. Medicine. Read Article


Postural Tachycardia Syndrome (POTS) Is Not Caused by Deconditioning. 2016. Pulmonary Circulation.  Read Article


Dermatological Manifestations of Postural Tachycardia Syndrome Are Common and Diverse. 2016. Journal of Clinical Neurology.  Read Article


Sleep disorders in patients with postural orthostatic tachycardia syndrome. 2016. Clinical Autonomic Research.  Read Article


A profile of patients with postural tachycardia syndrome and their experience of healthcare in the UK. 2016. The British Journal of Cardiology.  Read Article


Manifestations of Anxiety Explaining Tachycardia and Hypertension in a Patient with POTS. 2015. Family Medicine and Medical Science Research.  Read Article


A Case Report and Review of Postural Orthostatic Tachycardia Syndrome in Pregnancy. 2015. AJP Reports.  Read Article


Easily Missed: Resistant Postural Orthostatic Tachycardia Syndrome in a Hypermobile Young Man. 2015. Rheumatology.  Read Article


Quantitative Scale for Grading of Cardiovascular Autonomic Reflex Tests and Small Fibers from Skin Biopsies (QASAT). 2015. Journal of Neurological Disorders.  Read Article


Menstrual cycle phase does not affect sympathetic neural activity in women with postural orthostatic tachycardia syndrome. 2015. The Journal of Physiology.  Read Article


Autonomic activity and biomarker behavior in supine position and after passive postural stress in different orthostatic tachycardia syndromes. 2015. Portuguese Journal of Cardiology. Read Article


Reversible postural orthostatic tachycardia syndrome. 2015. World Journal of Clinical Cases.  Read More


Disturbances of gastrointestinal transit and autonomic functions in postural orthostatic tachycardia syndrome. 2015. Neurogastrolenterol Motil.  Read Article


A survey-based analysis of symptoms in patients with postural orthostatic tachycardia syndrome. 2015. Baylor Medical Center Proceedings.  Read More


Manifestations of Anxiety? Explaining Tachycardia and Hypertension in a Patient with POTS. 2015.  Read More

Mechanism of choline deficiency and membrane alteration in postural orthostatic tachycardia syndromeprimary skinfibroblasts. 2015. The FASEB Journal.  Read More

2015 Heart Rhythm Society Expert Consensus Statement on the Diagnosis and Treatment of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia, and Vasovagal Syncope. 2015. Heart Rhythm Society.  Read More


A survey-based analysis of symptoms in patients with postural orthostatic tachycardia syndrome. 2015. Baylor University Medical Center Proceedings.  Read Article


Structural brain abnormalities in postural tachycardia syndrome: A VBM-DARTEL study. 2015. Frontiers.  Read Article


Clinical classification and neuro-vestibular evaluation in chronic dizziness. 2015. Clinical Neurophysiology.  Read Article


Take a Stand: A neurologic disorder known as POTS causes dizziness and fainting—and frustration, due to lack of awareness and inadequate treatment. 2015. Neurology Now.  Read Article


Autonomic dysfunction in women with polycystic ovary syndrome. 2015. Iran Journal of Reproductive Medicine.  Read Article


A double-blind placebo-controlled cross-over study of the vascular effects of midodrine in neuropathic compared with hyperadrenergic postural tachycardia syndrome. 2014. Clinical Science (London).  Read Article


Postural tachycardia syndrome is associated with significant symptoms and functional impairment predominantly affecting young women: a UK perspective. 2014. British Medical Journal.  Read Article


Acute Hemodynamic Effects of a Selective Serotonin Reuptake Inhibitor in Postural Tachycardia Syndrome: A Randomized, Crossover Trial. 2014. Journal of Psychopharmacology.  Read Article


Postural Tachycardia Syndrome and Inappropriate Sinus Tachycardia: Role of Autonomic Modulation and Sinus Node Automaticity. 2014. Journal of the American Heart Association.  Read Article


Sleep Disturbances and Autonomic Dysfunction in Patients with Postural Orthostatic Tachycardia Syndrome. 2014. Frontiers in Neurology.  Read Article


Cognitive function, health-related quality of life, and symptoms of depression and anxiety sensitivity are impaired in patients with the postural orthostatic tachycardia syndrome (POTS). 2014. Frontiers in Physiology.  Read Article


Autoimmune Basis for Postural Tachycardia Syndrome. 2014. Journal of the American Heart Association. Read Article


Postural Orthostatic Tachycardia Syndrome: A Dermatologic Perspective and Successful Treatment with Losartan. 2014. The Journal of Clinical and Aesthetic Dermatology.  Read Article


A Tale of Two Syndromes: Lyme Disease Preceding Postural Orthostatic Tachycardia Syndrome. 2014. Annals of Noninvasive Cardiology.  Read Article


Sympathetic dysfunction in vasovagal syncope and the postural orthostatic tachycardia syndrome. 2014. Frontiers in Physiology.  Read Article


Neuronal and hormonal perturbations in postural tachycardia syndrome. 2014. Review Article. Frontiers.   Read Article


Confounders of Vasovagal Syncope: Postural Tachycardia Syndrome. 2013. Cardiology Clinicians.  Read Article


Effects of Norepinephrine Reuptake Inhibition on Postural Tachycardia Syndrome. 2013. Journal of the American Heart Association.  Read Article


Gastric Emptying in Postural Tachycardia Syndrome: A Preliminary Report. 2013. Clinical Autonomic Research.  Read Article


Structural and Functional Small Fiber Abnormalities in the Neuropathic Postural Tachycardia Syndrome. 2013. Plos One.  Read Article


What is brain fog? An evaluation of the symptom in postural tachycardia syndrome. 2013. Clinician Autonomic Research.  Read Article


Neurohumoral and haemodynamic profile in postural tachycardia and chronic fatigue syndromes. 2012. Clinical Science (London).  Read Article


Diagnosis and management of postural orthostatic tachycardia syndrome: A brief review. 2012. Journal of Geriatric Cardiology.  Read Article


Postural Tachycardia Syndrome: A Heterogeneous and Multifactorial Disorder. 2012. Proceedings of Mayo Clinic.  Read Article


Mechanisms of sympathetic regulation in orthostatic intolerance. 2012. Journal of Applied Physiology.  Read Article


Increasing orthostatic stress impairs neurocognitive functioning in chronic fatigue syndrome with postural tachycardia syndrome. 2012. Clinical Science.  Read Article


Sleep Disturbances and Diminished Quality of Life in Postural Tachycardia Syndrome. 2011. Journal of Clinical Sleep Medicine.  Read Article


Postural orthostatic tachycardia syndrome following Lyme disease. 2011. Cardiology Journal.  Read Article


Comparative Clinical Profile of Postural Orthostatic Tachycardia Patients With and Without Joint Hypermobility Syndrome. 2010. Indian Pacing Electrophysiology Journal.  Read Article


Autonomic Dysfunction Presenting as Postural Orthostatic Tachycardia Syndrome in Patients with Multiple Sclerosis. 2010. International Journal of Medical Sciences.  Read Article


Effect of Pregnancy on Postural Tachycardia Syndrome. 2010. Mayo Clinic Proceedings.  Read Article

Menstrual Cycle Affects Renal-Adrenal and Hemodynamic Responses During Prolonged Standing in the Postural Orthostatic Tachycardia Syndrome. 2010. Hypertension.  Read Article


Postural tachycardia syndrome (POTS). 2009. Journal of Cardiovascular Electrophysiology.  Read Article


Defects in Cutaneous Angiotensin-Converting Enzyme 2 and Angiotensin-(1-7) Production in Postural Tachycardia Syndrome. 2009. Hypertension.  Read Article


Postural Tachycardia Syndrome. 2008. Circulation.   Read Article


Postural orthostatic tachycardia syndrome is an under-recognized condition in chronic fatigue syndrome. 2008. QMJ: An International Journal of Medicine.   Read Article


Angiotensin II type 1 receptor blockade corrects cutaneous nitric oxide deficit in postural tachycardia syndrome. 2008. American Journal of Physiology - Heart and Circulatory Physiology.   Read Article


Reduced central blood volume and cardiac output and increased vascular resistance during static handgrip exercise in postural tachycardia syndrome. 2007. American Journal of Physiology - Heart and Circulatory Physiology.  Read Article


The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management. 2006. Indian Pacing Electrophysiology Journal.   Read Article


Postural hypocapnic hyperventilation is associated with enhanced peripheral vasoconstriction in postural tachycardia syndrome with normal supine blood flow. 2006. American Journal of Physiology - Heart and Circulatory Physiology.   Read Article


Hyperadrenergic Postural Tachycardia Syndrome in Mast Cell Activation Disorders. 2005. Hypertension.   Read Article


Fludrocortisone Acetate to Treat Neurally Mediated Hypotension in Chronic Fatigue Syndrome: A Randomized Controlled Trial. 2001. The Journal of the American Medical Association.  Read Article


The Neuropathic Postural Tachycardia Syndrome. 2000. New England Journal of Medicine.  Read Article


Chronic Orthostatic Intolerance: A Disorder With Discordant Cardiac and Vascular Sympathetic Control. 1998. Circulation.  Read Article