Pediatric/Adolescent POTS Articles

These articles appear in peer reviewed, scientific journals and are written by those active in researching POTS and other forms of dysautonomia.  When reading journal articles, it can be helpful to focus mainly on the abstract, introduction/background, and discussion section of the paper to get the main idea of the paper.


researchCardiac Responses to Exercise Distinguish Postural Tachycardia Syndrome Variants. 2016. Physiological Reports.  Read Article


Baroflex Sensitivity Predicts Short-Term Outcome of Postural Tachycardia Syndrome in Children. 2016. Plos One. Read Article


Pathogenesis and Individualized Treatment for Postural Tachycardia Syndrome in Children. 2016. Chinese Medical Journal.  Read Article


Use of an Allostatic Neurotechnology by Adolescents with Postural Orthostatic Tachycardia Syndrome (POTS) is associated with Improvements in Heart Rate Variability and Changes in Temporal Lobe Electrical Activity. 2016. Experimental Brain Research.  Read Article


Interdisciplinary Treatment of Maladaptive Behaviors Associated with Postural Orthostatic Tachycardia Syndrome (POTS): A Case Report. 2015. Journal of Clinical Psychology in Medical Settings. Read Article


Syncope in Children and Adolescents. 2015. Adolscent Medicine.  Read Article


Complex Regional Pain Syndrome and Dysautonomia in a 14-Year-Old Girl Responsive to Therapeutic Plasma Exchange. 2015. Journal of Clinical Apheresis. Read Article


Plasma C-Type Natriuretic Peptide as a Predictor for Therapeutic Response to Metoprolol in Children with Postural Tachycardia Syndrome. 2015. Plos One.  Read Article


Cognitive dysfunction in postural tachycardia syndrome. 2015. Clinical Science (London). Read Article


A cross-sectional study on upright heart rate and BP changing characteristics: basic data for establishing diagnosis of postural orthostatic tachycardia syndrome and orthostatic hypertension. 2015. British Medical Journal.  Read Article


Suspected side effects to the quadrivalent human papilloma vaccine. 2015. Danish Medical Journal.  Read Article


Use of an allostatic neurotechnology by adolescents with postural orthostatic tachycardia syndrome (POTS) is associated with improvements in heart rate variability and changes in temporal lobe electrical activity. 2015. Experimental Brain Research.  Read Article


Postural tachycardia syndrome is associated with significant symptoms and functional impairment predominantly affecting young women: a UK perspective. 2014. British Medical Journal Open.  Read Article


Postural Orthostatic Tachycardia Syndrome (POTS) and Vitamin B12 Deficiency in Adolescents. 2014. Pediatrics.  Read Article


High flow variant postural orthostatic tachycardia syndrome amplifies the cardiac output response to exercise in adolescents. 2014. Physiological Reports.  Read Article


Risk Factors for Postural Tachycardia Syndrome in Children and Adolescents. 2014. PLOS ONE.  Read Article


Peripheral Sympathetic Nerve Dysfunction in Adolescent Japanese Girls Following Immunization with the Human Papillomavirus Vaccine. 2014. Internal Medicine.  Read Article

Orthostatic plasma norepinephrine level as a predictor for therapeutic response to metoprolol in children with postural tachycardia syndrome. 2014. Journal of Translational Medicine.  Read Article


Postural Orthostatic Tachycardia Syndrome (POTS) and Vitamin B12 Deficiency in Adolescents. 2014. Pediatrics.  Read Article


Chest Pain and Syncope in Children: A Practical Approach to the Diagnosis of Cardiac Disease. 2014. Journal of Pediatrics.  Read Article


A double-blind placebo-controlled cross-over study of the vascular effects of midodrine in neuropathic compared with hyperadrenergic postural tachycardia syndrome. 2014. Clinical Science.  Read Article


Higher postural heart rate increments on head-up tilt correlate with younger age but not orthostatic symptoms. 2013. Journal of Applied Physiology.  Read Article


Low iron storage in children with tilt positive neurally mediated syncope. 2013. World Journal of Pediatrics. Read Article

Orthostatic symptoms does not always manifest during tilt-table test in pediatric postural orthostatic tachycardia syndrome patient. 2013. Korean Journal of Pediatrics.  Read Article


What is brain fog? An evaluation of the symptom in postural tachycardia syndrome. 2013. Clinical Autonomic Research. Read Article

Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome. 2013. Frontiers in Physiology. Read Article

Common Syndromes of Orthostatic Intolerance. 2013. Pediatrics.  Read Article


Evidence of Small-Fiber Polyneuropathy in Unexplained, Juvenile-Onset, Widespread Pain Syndromes. 2013. Pediatrics.   Read Article


Midregional Pro-Adrenomedullin as a Predictor for Therapeutic Response to Midodrine Hydrochloride in Children With Postural Orthostatic Tachycardia Syndrome. 2012. Journal of the American College of Cardiology.  Read Article


Postural neurocognitive and neuronal activated cerebral blood flow deficits in young chronic fatigue syndrome patients with postural tachycardia syndrome. 2012. American Journal of Physiology.  Read Article


Gastric Electrical Activity Becomes Abnormal in the Upright Position in Patients With Postural Tachycardia Syndrome. 2010. Journal of Pediatric Gastroenterology & Nutrition.  Read Article


Decreased upright cerebral blood flow and cerebral autoregulation in normocapnic postural tachycardia syndrome. 2009. American Journal of Physiology - Heart and Circulatory Physiology.  Read Article


Postural Tachycardia Syndrome and Reflex Syncope: Similarities and Differences. 2009. Journal of Pediatrics.  Read Article


A Matched Case Control Study of Orthostatic Intolerance in Children/Adolescents With Chronic Fatigue Syndrome. 2008. Pediatric Research.  Read Article


Orthostatic Intolerance and Gastrointestinal Motility in Adolescents With Nausea and Abdominal Pain. 2008. Journal of Pediatric Gastroenterology & Nutrition.  Read Article


Persistent splanchnic hyperemia during upright tilt in postural tachycardia syndrome. 2006. American Journal of Physiology - Heart and Circulatory Physiology.  Read Article


Pediatric Autonomic Disorders. 2006. Pediatrics.  Read Article


Postural hypocapnic hyperventilation is associated with enhanced peripheral vasoconstriction in postural tachycardia syndrome with normal supine blood flow. 2006. American Journal of Physiology - Heart and Circulatory Physiology.   Read Article


Splanchnic hyperemia and hypervolemia during Valsalva maneuver in postural tachycardia syndrome. 2005. American Journal of Physiology - Heart and Circulatory Physiology. Read Article


Decreased Microvascular Nitric Oxide–Dependent Vasodilation in Postural Tachycardia Syndrome. 2005. Circulation.  Read Article


Relation of Postural Vasovagal Syncope to Splanchnic Hypervolemia in Adolescents. 2004. Circulation.  Read Article


Reflex syncope in children and adolescents. 2004. Heart.  Read Article


Syncope in childhood. 2003. Archives of Disease in Childhood.  Read Article


Microvascular Filtration Is Increased in Postural Tachycardia Syndrome. 2002. Circulation.  Read Article


Clinical and Physiological Effects of an Acute α-1 Adrenergic Agonist and a β-1 Adrenergic Antagonist in Chronic Orthostatic Intolerance. 2002. Circulation.  Read Article


Pooling in Chronic Orthostatic Intolerance: Arterial Vasoconstrictive but not Venous Compliance Defects. 2002. Circulation.  Read Article


Orthostasis fails to produce active limb venoconstriction in adolescents. 2001. Journal of Applied Physiology.  Read Article


Autonomic Abnormalities in Children With Functional Abdominal Pain: Coincidence or Etiology? 2001. Journal of Pediatric Gastroenterology & Nutrition.   Read Article


Reflex vascular defects in the orthostatic tachycardia syndrome of adolescents. 2001. Journal of Applied Physiology.  Read Article


Autoantibodies to Ganglionic Acetylcholine Receptors in Autoimmune Autonomic Neuropathies. 2000. New England Journal of Medicine.  Read Article


Autonomic Nervous System Dysfunction in Adolescents with Postural Orthostatic Tachycardia Syndrome and Chronic Fatigue Syndrome Is Characterized by Attenuated Vagal Baroreflex and Potentiated Sympathetic Vasomotion. 2000. Pediatric Research.  Read Article


Vascular perturbations in the chronic orthostatic intolerance of the postural orthostatic tachycardia syndrome. 2000. Journal of Applied Physiology.  Read Article